Essays

• September 28, 2013 - Boundary-Breaking Evolution via B Lymphocyte Clonal Selection in Response to HIV-1
• August 24, 2013 - The Case for Applying Negative Selection to Thoughts on Clonal Selection by Prospect Magazine's Number One 2013 "World Thinker"
• July 30, 2013 - The Challenge of Breaking the Meta-Code: Context and the Meaning of the Genome
• June 28, 2013 - Phenotypic and Genotypic Variation of a Fungal Pathogen Powered by Codon Ambiguity and Degenerate Translation
• May 28, 2013 - Goldilocks and the Three Phenotypes: Insights from the Conservation of Mycobacterial Pathogenesis between Zebrafish and Humans
• April 30, 2013 - Evolved Genetic Variation as a Guide to the Evolution of Therapy
• March 30, 2013 - The Power of Graur to Explode ENCODE Using Incision and Derision
• February 28, 2013 - Intelligent Design, the Resurfacing of a Pseudo-Theory
• January 28, 2013 - Are Viruses Alive?
• January 24, 2013 - A Possible Evolutionary Explanation for the Frequency of CCR5?32
• December 30, 2012 - Augmented Infection Control via Practical Pathogen Phylogenetics Based on Whole-Genome Sequencing
• November 30, 2012 - Another New Perspective on Bacterial Evolution by Gene Duplication
• October 31, 2012 - Genomic Analysis of a Bacterial Evolutionary Pathway Underlying a Phenotypic Innovation
• September 30, 2012 - Influenza A Virus: Is Virulence Attributable to Virulence Factors?
• August 28, 2012 - Potential Influence of Winner-Take-All Markets on Human Evolution and Medicine
• July 22, 2012 - A Personal Perspective on Prospects for Personalized Medicine
• June 28, 2012 - An Ecological and Evolutionary Perspective on Gastrointestinal Health
• May 30, 2012 - The Focus of Selection, the Locus of Response, and Epigenetic Evasion
• April 30, 2012 - Levels of Selection, Logical Schemes, Selfish Genes, and Misleading Memes
• March 30, 2012 - Parallel Evolution Guides Identification of Pathogenic Pathogen Mutations
• February 28, 2012 - Phenotypic Variation Due to Epigenetic and Environmental Variation
• January 24, 2012 - Of Sickle Cells, Cytoskeletons, Cell Surfaces, and Selection
• December 28, 2011 - Evolutionary Variation as a 'Lead Compound'
• November 30, 2011 - Methodological Foundations for Evolution by Engineered Variation and Selection
• October 26, 2011 - Humoral Immune Responses to HIV-1: Fighting Evolution with Evolution
• September 28, 2011 - Evolutionary and Ecological Factors in Influenza A Virus Spread
• August 31, 2011 - Possible Degeneracy in Genotype-Phenotype Relationships due to DNA-RNA Sequence Disparity
• July 22, 2011 - Autism and Acquired Misapprehensions about Heritability
• June 28, 2011 - History of the Immunological Thread in the Fabric of Evolutionary Medicine
• May 30, 2011 - Continuous In Vitro Directed Evolution of Macromolecules
• April 30, 2011 - Accessible Account of the Complexity of Complexity
• March 24, 2011 - A Genomic Perspective on Pathogen Adaptation to Antibiotics and Vaccines
• February 22, 2011 - Man, Machine, and Metaphorical Misdirection
• January 30, 2011 - Considering Cellular Complexity
• December 28, 2010 - Chemotherapy-Associated Evolution in Melanoma
• November 30, 2010 - Evolutionary Erosion of Anti-Microbial Magic
• October 29, 2010 - Cancer Chemotherapy Informed by Evolutionary Considerations
• September 24, 2010 - Genetic Origins of Common Human Diseases
• August 26, 2010 - From Ethereal to Material: Abstract Origins of Practical Genomic Analysis
• July 24, 2010 - Evolutionary Origins of a Potent Broadly-Neutralizing Antibody to HIV-1
• July 7, 2010 - Hogwash about the singularity is here
• June 23, 2010 - Amino Acid Gymnastics and the Evolution of Influenza Virus Resistance to Oseltamivir
• May 31, 2010 - Original, Concise, and Incisive Analysis of Key Evolutionary Concepts
• May 27, 2010 - Genes that Promote Self-Promotion
• May 25, 2010 - Autism conceptualized: "cloud" vs. "spectrum."
• May 3, 2010 - Autism and the media
• April 30, 2010 - A Medical Application of Phylogenetic Analysis
• April 6, 2010 - Major obstacles for adults with autism
• March 26, 2010 - Selection, Epistasis, and Genotype-Phenotype Relationships
• February 18, 2010 - Immunoselective Subversion of Therapy for Myeloid Cancer
• January 20, 2010 - Reflection on Detection of Positive Selection
• December 30, 2009 - Bugs versus Features in Evolution: Misacylation of tRNA
• November 28, 2009 - Selection and the Context-Dependence of Phenotypic Optimization
• October 22, 2009 - Therapeutic Selection
• September 14, 2009 - The Prominence and Pertinence of Pleiotropy
• July 22, 2009 - Too much optimism at NIH
• July 21, 2009 - Growing Complexities in Relating Genotype to Phenotype
• June 15, 2009 - Protein Dynamics and Evolution
• May 14, 2009 - Application of Selection to a Clinically-Important Infectious Disease
• April 23, 2009 - MHC Restriction and Host-Pathogen Co-Evolution
• March 18, 2009 - Boundaries of Categories, Categories of Boundaries, and Evolution
• February 5, 2009 - Evolved challenges to the innate/adaptive immunity dichotomy

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